SciPost Phys. Lect. Notes 87 (2024) ·
published 23 September 2024
|
· pdf
At the 2023 Les Houches Summer School on Theoretical Biological Physics, several students asked for some background on information theory, and so we added a tutorial to the scheduled lectures. This is largely a transcript of that tutorial, lightly edited. It covers basic definitions and context rather than detailed calculations. We hope to have maintained the informality of the presentation, including exchanges with the students, while still being useful.
SciPost Phys. Lect. Notes 84 (2024) ·
published 15 August 2024
|
· pdf
Theoretical physicists have been fascinated by the phenomena of life for more than a century. As we engage with more realistic descriptions of living systems, however, things get complicated. After reviewing different reactions to this complexity, I explore the optimization of information flow as a potentially general theoretical principle. The primary example is a genetic network guiding development of the fly embryo, but each idea also is illustrated by examples from neural systems. In each case, optimization makes detailed, largely parameter-free predictions that connect quantitatively with experiment.
