SciPost logo

Ambitions for theory in the physics of life

William Bialek

SciPost Phys. Lect. Notes 84 (2024) · published 15 August 2024

Part of the 2023-07: Theoretical Biological Physics 2023 Collection in the Les Houches Summer School Lecture Notes Series.

Abstract

Theoretical physicists have been fascinated by the phenomena of life for more than a century. As we engage with more realistic descriptions of living systems, however, things get complicated. After reviewing different reactions to this complexity, I explore the optimization of information flow as a potentially general theoretical principle. The primary example is a genetic network guiding development of the fly embryo, but each idea also is illustrated by examples from neural systems. In each case, optimization makes detailed, largely parameter-free predictions that connect quantitatively with experiment.

Cited by 1

Crossref Cited-by

Author / Affiliation: mappings to Contributors and Organizations

See all Organizations.
Funders for the research work leading to this publication